Diethyl phosphite 762-04-9 CAS NO.762-04-9

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Introduction：

  This product is colorless oily liquid, flammable, b.p.187～188℃, n20D1.4080, relative density 1.072, insoluble in water, decomposes in hot water, soluble in organic solvents such as alcohol and ether.

Diethyl phosphite Basic information

Product Name:	Diethyl phosphite
Synonyms:	diethylacidphosphite;diethylfosfit;Ethyl phosphonate ((EtO)2HPO);Diethyl phosphite,98%;Phosphorous acid diethyl;Phosphorous acid hydrogen diethyl;Phosphonic acid diethyl;Phosphonic Acid Diethyl Ester Diethyl Phosphonate Phosphorous Acid Diethyl Ester
CAS:	762-04-9
MF:	C4H11O3P
MW:	138.1
EINECS:	212-091-6
Product Categories:	Organic Building Blocks;Organic Phosphates/Phosphites;Catalysis and Inorganic Chemistry;Phosphorus Compounds;Phosphorus Precursors;organophosphorus compound;Pharmaceutical Intermediates;Building Blocks;Chemical Synthesis;Organic Building Blocks;Organic Phosphates/Phosphites;Phosphorus Compounds
Mol File:	762-04-9.mol

Diethyl phosphite Chemical Properties

Melting point	-70 °C
Boiling point	50-51 °C/2 mmHg (lit.)
density	1.072 g/mL at 25 °C (lit.)
refractive index	n20/D 1.407(lit.)
Fp	180 °F
form	Liquid
color	Colorless
Specific Gravity	1.072
Water Solubility	miscible (hydrolysis)
Sensitive	Moisture Sensitive
Hydrolytic Sensitivity	7: reacts slowly with moisture/water
BRN	605759
Stability:	Stable. Incompatible with strong oxidizing agents, strong acids, acid chlorides, strong bases. May decompose on exposure to moisture. Combustible.
InChIKey	MJUJXFBTEFXVKU-UHFFFAOYSA-N
CAS DataBase Reference	762-04-9(CAS DataBase Reference)
NIST Chemistry Reference	Phosphonic acid, diethyl ester(762-04-9)
EPA Substance Registry System	Diethyl phosphite (762-04-9)

Safety Information

Hazard Codes	Xi
Risk Statements	36/37/38-43
Safety Statements	26-36/37/39-37/39-28-27
WGK Germany	1
RTECS	TG7875000
F	10-13-21
TSCA	Yes
HS Code	29209014
Hazardous Substances Data	762-04-9(Hazardous Substances Data)

MSDS Information

Provider	Language
Diethyl hydrogen phosphonate	English
SigmaAldrich	English
ALFA	English

Diethyl phosphite Usage And Synthesis

Chemical Properties	colourless liquid
Uses	Diethyl phosphite (DEPI) is a versatile reactive intermediate used in the production of various phosphorus based substances. It may be used to prepare the nickel chloride-diethyl phosphite system, efficient catalyst for the cross-coupling reaction between various functionalized arylzinc halides and aryl bromides, triflates and activated chlorides. It may be used: in the stereoselective synthesis of β-fluorinated alkylphosphonates Used in synthesis of homoallylic bromide Used in synthesis of series of carbazole-based α-aminophosphonates used as an extraction agent and phosphate intermediate. Used in synthesis of pesticides kitazine and phosethyl-Al as well as synthetic O, O-diethyl phosphoryl chloride. used for the synthesis of plasticizers, flame retardants, etc. Diethyl phosphite is reported to be chemical warfare agent (CWA) simulant, simulant for nerve agents sarin, soman, tabun, and VX.
Uses	Diethyl phosphite is precursor used for the synthesis of various organophosphorus compounds. used to prepare the nickel chloride-diethyl phosphite system, efficient catalyst for the cross-coupling reaction between various functionalized arylzinc halides and aryl bromides, triflates and activated chlorides.
Definition	ChEBI: A phosphonic ester that is the diethyl ester of phosphonic acid.
Synthesis Reference(s)	Synthetic Communications, 18, p. 665, 1988 DOI: 10.1080/00397918808077352
Synthesis Reference(s)	Tetrahedron Letters, 29, p. 3327, 1988 DOI: 10.1016/0040-4039(88)85153-0
General Description	Diethyl phosphite is reported to be chemical warfare agent (CWA) simulant, simulant for nerve agents sarin, soman, tabun, and VX.

Diethyl phosphite Preparation Products And Raw materials

Raw materials

Nitrogen-->Stirring vessel-->Oil pump

Preparation Products

(S)-(-)-7,7'-BIS[DI(3,5-DIMETHYLPHENYL)PHOSPHINO]-2,2',3,3'-TETRAHYDRO-1,1'-SPIROBIINDANE-->(R)-7,7'-BIS(DIPHENYLPHOSPHINO)-1,1'-SPIROBIINDANE-->Triethyl phosphite-->(R)-(+)-7,7'-BIS(DIPHENYLPHOSPHINO)-2,2',3,3'-TETRAHYDRO-1,1'-SPIROBIINDANE-->(R)-(+)-7,7'-BIS[DI(4-METHYLPHENYL)PHOSPHINO]-2,2',3,3'-TETRAHYDRO-1,1'-SPIROBIINDANE-->(S)-7,7'-Bis[di(p-methylphenyl)phosphino]-1,1'-spirobiindane ,97%-->4,4'-Vinylenedipyridine-->Iprobenfos-->(S)-(-)-2,2'-BIS(DI-P-TOLYLPHOSPHINO)-1,1'-BINAPHTHYL-->(R)-(+)-2,2'-Bis(di-p-tolylphosphino)-1,1'-binaphthyl-->Diphenylphosphine oxide-->Fosetyl aluminum-->Foscarnet sodium-->Ethephon-->Diethyl chlorophosphate-->FOSAMINE AMMONIUM-->ETHYLPHOSPHONIC ACID-->Diethyl 3,5-di-tert-butyl-4-hydroxybenzyl phosphate-->PARAOXON-->DIETHYL PHOSPHATE-->2,2'-(1,2-Ethenediyldi-4,1-phenylene)bisbenzoxazole-->SODIUM O,O-DIETHYLTHIOPHOSPHATE

Function:

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    Tianeptine has a variety of effects on the body, including motivation enhancement, anxiety suppression, cognitive euphoria, focus enhancement, rejuvenation, and cognitive fatigue.

Application:

1) Tianeptine Improves Depressive Symptoms.

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3) Tianeptine Benefits Memory and Learning.

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Specification:

 

 

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   Production Inspection Process:

Our Group service includes regular and thorough inspections throughout the manufacturing process, eliminating the need to employ additional quality control inspectors.

- Raw material before any production begins

- Pre-production samples to ensure specifications are being met

- In-process to confirm that standards are maintained

- Pre-shipping to ensure that the product arrives to the customer exactly as expected and is packaged

correctly to prevent any damage in transit.

 

   

     We can help operating split shipments, meeting the factory minimum quantity but ship them in 2 or 3 shipments with required gaps among. This allows you to move stock through your business without taking up space and capital.

We will arrange the subsequent shipments from our factory to your warehouse.

We can consolidate your small orders from multiple factories, delivering all at the same time to you or your customers,using the most cost-effective route available. At the time of order placement, we will offer details to you about the volume of each component part and what size container will be used.

 

    We can offer the complete package from concept to delivery; arranging everything up until products arrive at your own door or distribution hub.

   Delivery can be offered.

    - Utilizing your own freight-forwarder

    - FOB to a port in China

    - CIF to a port near you

   Whether you have your own freight-forwarder or you would like to organize shipment; whether you require delivery FOB in China or CIF to a port near you, we are glad to quote and supply whichever way you choose. Please feel free to discuss all options with us.

 

 

 

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