Anti-inflammatory analgesic drugs Indometacin CAS:53-86-1 CAS NO.53-86-1

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Min.Order: 1 Kilogram
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Available Specifications:
99%(1-9)Kilogram46/Kilogram1USD99%(10-20)Kilogram42/Kilogram10USD

Product Details

Keywords

Indometacin
53-86-1
Acemetacin-->indomethacin farnesil

Quick Details

ProName: Anti-inflammatory analgesic drugs Indo...
CasNo: 53-86-1
Molecular Formula: C19H16ClNO4
Appearance: White powder
Application: 1.The product is anti-inflammatory, ...
DeliveryTime: Shipped in 15 days after payment
PackAge: according to customers' requirements
Port: China main port
ProductionCapacity: 10000 Metric Ton/Month
Purity: 99%
Storage: Store at RT.
Transportation: Air, sea, land transport
LimitNum: 1 Kilogram
Related Substances: 0
Residue on Ignition: 0.1% max
Heavy Metal: 10ppm max
Valid Period: 2 years

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Details

Introduction:

Indomethacin is a kind of stronger corticoid anti-inflammatory and antipyretic and analgesic, by inhibiting cyclooxygenase reducing the synthesis of prostaglandin (PG), to prevent the formation of the nere impulses, inflammation tissue inhibiting inflammatory reaction, including inhibition of leukocyte chemotaxis and lysosomal enzyme release, etc., and produce antipyretic, analgesic and anti-inflammatory effects.Clinical is mainly used for the salicylic acid, drugs are less tolerance or curative effect is not obvious in the acute and chronic rheumatic or rheumatoid arthritis, ankylosing spondylitis, slippery bursa phlogistic, tenosynovitis, articular capsulitis, osteoarthritis and acute gout and cancerous pain, etc.In recent years, the researchers try to use indomethacin biliary colic, dysmenorrhea, migraine, glomerulonephritis, polyuria, salmonella gastroenteritis, orthostatic hypotension, bart syndrome and so on, all have good curative effect.It can also be used to treat eye pigment meningitis, keratitis, scleritis, glaucoma and fever caused by cancer or other difficult to control the fever. Dermatologist for lupus erythematosus (sle), white plug syndrome, scleroderma, nodular erythema, herpes zoster, joint type of psoriasis, etc. photosensitive dermatitis induced by topical treatment of eczema, allergic dermatitis, and local pain.

Function:

Indometacin (INN and BAN) or indomethacin (AAN, USAN and former BAN) is a non-steroidal anti-inflammatory drug(NSAID) commonly used as a prescription medication to reduce fever, pain, stiffness, and swelling. It works by inhibiting the production of prostaglandins, molecules known to cause these symptoms.

Main Application:

Clinical indications for indometacin include:

1.ankylosing spondylitis

2.arthritic gout

3.Bartter syndrome

4.bursitis

5.cryoglobulinemia

6.dysmenorrhea (menstrual cramps)

7.fever and pain associated with malignant diseases (especially tumor fever associated 8.with liver involvement, lymphogranulomatosis)

9.headaches caused by the Valsalva maneuver

10.hemicrania continua

11.hypnic headache

12.juvenile arthritis

13.migraine

14.nephrogenic diabetes insipidus (prostaglandin inhibits vasopressin's action in the kidney)

15.osteoarthritis

16.Paget's disease of bone

17.paroxysmal hemicrania

18.patent ductus arteriosus

19.pericarditis

20.primary exertion headache

21.primary stabbing headaches

22.pseudogout

23.psoriatic arthritis

24.reactive arthritis

25.renal colic (pain due to kidney stones)

26.retinopathy of prematurity

27.rheumatoid arthritis

28.tendinitis

29.trigeminal autonomic cephalgias

Indometacin is suitable for relieving heat and relieving inflammatory pain, so it can be used for acute, chronic rheumatoid arthritis, gouty arthritis and cancer pain (western medicine).It can also be used for bursitis, tenosynovitis and joint bursitis.Antiplatelet aggregation can prevent thrombosis.

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- Raw material before any production begins

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