Antibiotic,Sulfanilamide,cas:63-74-1 CAS NO.63-74-1
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- Product Details
Keywords
- 63-74-1
- Sulfanilamide
- Prontalbin
Quick Details
- ProName: Antibiotic,Sulfanilamide,cas:63-74-1
- CasNo: 63-74-1
- Molecular Formula: C6H8N2O2S
- Appearance: white powder
- Application: The product is an important intermedia...
- DeliveryTime: Shipped in 15 days after payment
- PackAge: according to customers' requirements
- Port: China main port
- ProductionCapacity: 10000 Metric Ton/Month
- Purity: %
- Storage: 0-6°C
- Transportation: Air, sea, land transport
- LimitNum: 1 Kilogram
Superiority
Sulfanilamide is an organic sulfur compound structurally similar to p-aminobenzoic acid (PABA) with antibacterial property. Sulfanilamide competes with PABA for the bacterial enzyme dihydropteroate synthase, thereby preventing the incorporation of PABA into dihydrofolic acid, the immediate precursor of folic acid. This leads to an inhibition of bacterial folic acid synthesis and de novo synthesis of purines and pyrimidines, ultimately resulting in cell growth arrest and cell death.Without it, bacteria cannot replicate.
Mechanism of action: mechanism of action is to interfere with the synthesis of nucleic acids required for pathogenic microorganisms,making bacteria lack of nutrition and stop the growth, development and reproduction, having suppression killing effect on hemolytic streptococcus, staphylococcus and meningococcal.
Pharmacodynamics: Oral easily absorbed from the gastrointestinal tract, widely distributed in the body, can penetrate the blood-brain barrier into the brain tissue, and can penetrate the placental barrier into the fetus. Rapid excretion, mainly excreted in metabolites from kidney.
Clinical application: Mainly used for trauma infection caused by infection hemolytic streptococcus, staphylococcus, and local wound infections.
Details
Formula:C6H8N2O2S
Molecular Weight:172.20
CAS No.:63-74-1
EINECS:200-563-4
Density:1.427 g/cm3
Solubility:7.5 g/L at 25 °C
Melting Point:164-167 °C
Boiling Point:400.5 °C at 760 mmHg
Flash Point:196 °C
1. For the pharmaceutical industry, is the main raw material for the synthesis of sulfonamides
2. Used as a reagent for the determination of nitrite, also used in the pharmaceutical industry
3. For the synthesis of other sulfa drugs intermediates, even for wound disinfection
4. P-Aminobenzenesulfonamide is an intermediate of herbicide mulginsk, also an intermediate for pharmaceutical sulfonamides.
5. The product is an important intermediate sulfa drugs.
6. veterinary drugs, topical anti-inflammatory drugs, for analysis and detection.