anti-tumor drug ,Sorafenib tosylate,cas:475207-59-1 CAS NO.475207-59-1

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Product Details

Keywords

475207-59-1
Sorafenib tosylate
anti-tumor drug

Quick Details

ProName: anti-tumor drug ,Sorafenib tosylate,ca...
CasNo: 475207-59-1
Molecular Formula: C28H24ClF3N4O6S
Appearance: white powder
Application: Sorafenib Tosylate (Bay 43-9006, Nexav...
DeliveryTime: Shipped in 15 days after payment
PackAge: according to customers' requirements
Port: China main port
ProductionCapacity: 10000 Metric Ton/Month
Purity: %
Transportation: Air, sea, land transport
LimitNum: 50 Gram

Superiority

Sorafenib tosylate is a novel multi-target anti-tumor drug developed by Bayer Pharmaceuticals, Germany, which acts on both tumor cells and tumor blood vessels. It has a dual anti-tumor effect: it directly inhibits tumor cell proliferation by blocking the RAF/MEK/ERK-mediated cell signaling pathway, and also inhibits VEGF and platelet-derived growth factor (PDGF) receptors. Blocking the formation of tumor neovascularization, indirectly inhibiting the growth of tumor cells.

Details

Introduction:

Product name	Sorafenib tosylate
CAS	475207-59-1
Synonyms	SORAFENIB TOSYLATE;Sorafenib & its intermediates;Sorafinib mesylate;4-Methyl-3-((4-(3-pyridinyl)-2-pyrimidinyl)amino)-N-(5-(4-methyl-1H-imidazol-1-yl)-3-(trifluoromethyl)phenyl)benzamide monomethanesulfonate;Sorafenib Tosylate(Bay 43-9006,Nexavar);2-PyridinecarboxaMide, 4-[4-[[[[4-chloro-3-(trifluoroMethyl)phenyl]aMino]carbonyl]aMino]phenoxy]-N-Methyl-, 4-Methylbenzenesulfonate;Sorafenib Tosylate (Nexavar);Sorafenib (Nexavar)
Molecular formula	C28H24ClF3N4O6S
Molecular weight	637.0265696
Mol File	475207-59-1.mol
Appearance	White powder
EINECS number	641-758-8
Application	API

Function:

Used as a pharmaceutical intermediates.

It is used for the treatment of advanced liver cancer.

Sorafenib Tosylate (Bay 43-9006, Nexavar) is a small molecular inhibitor of VEGFR, PDGFR, c-Raf and B-Raf with IC50s of 18 nM, 10 nM, 3 nM and 15 nM, respectively.

Sorafenib Tosylate (Bay 43-9006) is a multikinase inhibitor of Raf-1, B-Raf and VEGFR-2 with IC50 of 6 nM, 22 nM and 90 nM, respectively

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Production Inspection Process:

Our Group service includes regular and thorough inspections throughout the manufacturing process, eliminating the need to employ additional quality control inspectors.

- Raw material before any production begins

- Pre-production samples to ensure specifications are being met

- In-process to confirm that standards are maintained

- Pre-shipping to ensure that the product arrives to the customer exactly as expected and is packaged

correctly to prevent any damage in transit.

We can help operating split shipments, meeting the factory minimum quantity but ship them in 2 or 3 shipments with required gaps among. This allows you to move stock through your business without taking up space and capital.

We will arrange the subsequent shipments from our factory to your warehouse.

We can consolidate your small orders from multiple factories, delivering all at the same time to you or your customers,using the most cost-effective route available. At the time of order placement, we will offer details to you about the volume of each component part and what size container will be used.

We can offer the complete package from concept to delivery; arranging everything up until products arrive at your own door or distribution hub.

Delivery can be offered.

- Utilizing your own freight-forwarder

- FOB to a port in China

- CIF to a port near you

Whether you have your own freight-forwarder or you would like to organize shipment; whether you require delivery FOB in China or CIF to a port near you, we are glad to quote and supply whichever way you choose. Please feel free to discuss all options with us.