China (Mainland)
Premiumsupplier 
Fast Delivery High Quality Nystatin CAS 1400-61-9 CAS NO.1400-61-9
- FOB Price: USD: 260.00-320.00 /Kilogram Get Latest Price
- Min.Order: 1 Kilogram
- Payment Terms: L/C,D/A,D/P,T/T,MoneyGram
- Available Specifications:
99%(1-50)Kilogram99%(51-100)Kilogram
- Product Details
Keywords
- 1400-61-9
- Nystatin
- Polyene antifungal drugs
Quick Details
- ProName: Fast Delivery High Quality Nystatin CA...
- CasNo: 1400-61-9
- Molecular Formula: C47H75NO17
- Appearance: White powder
- Application: Mainly used for Candida albicans infec...
- DeliveryTime: Within 3 workdays after payment
- PackAge: 1kg/BAG,25kg/DRUM,according to custom...
- Port: China main port
- ProductionCapacity: 10000 Metric Ton/Month
- Purity: 99%
- Storage: ?20°C
- Transportation: Air, sea, land transport
- LimitNum: 1 Kilogram
- Related Substances: 0
- Residue on Ignition: <0.5
- Heavy Metal: <0.003%
- Valid Period: 2 years
Superiority
Details
| Name: Nystatin |
| Synonyms: Nystain |
| C.A.S NO. : 1400-61-9 |
| Molecular formula: C47H75NO17 |
| Molecule weight: 926.10 |
| Specification: HPLC 99% |
| Characteristic: Yellow or slightly brownish powder |
| Boiling point: 400.2±14.0 °C at 760 mmHg |
| Density: 0.9±0.1 g/cm3 |
Nystatin is a polyene antifungal drug to which many molds and yeast infections are sensitive, including Candida.Cutaneous, vaginal, mucosal and esophageal. Candida infections usually respond well to treatment with nystatin.
Like amphotericin B and natamycin, nystatin binds to ergosterol, a major component of the fungal cell membrane. When present in sufficient concentrations, it forms pores in the membrane that lead to K+ leakage and death of the fungus.
1. Nystatin is often used as prophylaxis in patients who are at risk for fungal infections.
2. It is prescribed in units, with doses varying from 100,000 (for oral infections) to 1 million (for intestinal ones). As it is not absorbed from the gut, it is safe for oral use and does not have problems of drug interactions.
3. It is also used in cellular biology as an inhibitor of the lipid raft-caveolae endocytosis pathway on mammalian cells, at concentrations around 3 µg/mL.
4. In certain cases, nystatin has been used to prevent the spread of mold on objects such as works of art. For example, it was applied to wood panel paintings damaged as a result of the Arno River Flood of 1966 in Florence, Italy.
Nystatin is also used as a tool by scientists performing "perforated" patch-clamp electrophysiologic recordings of cells. When loaded in the recording pipette, it allows for measurement of electrical currents without washing out the intracellular contents, because it forms pores in the cell membrane that are permeable to only monovalent ions.
