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Hydroxyurea Immune inhibitors CAS NO.127-07-1
- FOB Price: USD: 35.00-50.00 /Kilogram Get Latest Price
- Min.Order: 1 Kilogram
- Payment Terms: L/C,D/A,D/P,T/T,
- Available Specifications:
98%(1-30)Kilogram98%(20-40)Kilogram
- Product Details
Keywords
- 127-07-1
- Immune inhibitors
- Ethyl carbamate
Quick Details
- ProName: Hydroxyurea Immune inhibitors
- CasNo: 127-07-1
- Molecular Formula: CH4N2O2
- Appearance: white powder
- Application: Antimetabolic anti-cancer drugs, which...
- DeliveryTime: Shipped in 15 days after payment
- PackAge: according to customers' requirements
- Port: China main port
- ProductionCapacity: 10000 Metric Ton/Month
- Purity: 99%
- Storage: 2-8°C
- Transportation: Air, sea, land transport
- LimitNum: 1 Kilogram
- Related Substances: 0
- Residue on Ignition: 0.10% max
- Heavy Metal: 8ppm
- Valid Period: 2 years
Superiority
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Details
Introduction:
Hydroxyurea is an anticancer drug for the treatment of chronic myeloid leukemia. It has been observed since the 1920s that hydroxyurea causes rabbits to produce giant erythrocyte blood cells similar to those of malignant anemia, and inhibits leukocyte production. It was found to inhibit L1210 mouse leukemia in 1963. Hydroxyurea can induce bacteria to produce a molecule that is toxic to itself and thus kill bacteria.
Hydroxyurea, also known as hydroxyurea, hydroxyurea, carbamoyl hydroxyurea, is a nucleoside diphosphate reductase inhibitor that prevents the reduction of nucleotides to deoxynucleotides and interferes with the biosynthesis of purine and pyrimidine bases. Selectively block DNA synthesis and partially inhibit the conversion of ribonucleic acid to deoxyribonucleotides. No blocking effect on RNA and protein synthesis. Hydroxyurea is a cycle-specific drug that is sensitive to S phase cells and can induce hematologic remission of chronic myeloid leukemia. Compared with the alkylating agents busulfan and melphalan, the incidence of secondary leukemia is low. The myelosuppressive effect of hydroxyurea lasts for several days to several weeks and is easier to control than alkylating agents. Clinically, hydroxyurea is suitable for the treatment of chronic myeloid leukemia, acute lymphocytic and acute non-lymphocytic leukemia with high cell count, spontaneous thrombocytosis, polycythemia vera, and retinoic acid syndrome for prevention of acute myeloid leukemia. For the treatment of sickle cell anemia with frequent pain episodes. In addition, hydroxyurea has a certain effect on the treatment of head and neck cancer, recurrent metastatic ovarian cancer, kidney cancer and the like.
Function:
1: Anti-metabolite anticancer drugs, mainly acting on the G1 and S phases of proliferating cells, have a retarding effect on the G1/S interface, and are cell-specific drugs.
2: Biochemical research
3: Anti-metabolite anticancer drugs, mainly acting on the G1 and S phases of proliferating cells, have a retarding effect on the G1/S interface, and are cell-specific drugs. Antitumor. The nucleoside reductase is inactivated by the formation of free nitric oxide and binding to tyrosine at the active site of the enzyme. This hinders the synthesis of deoxynucleotides. It is used therapeutically for the treatment of chronic myeloid leukemia, as well as for the treatment of metastatic ovarian cancer, primary squamous cell carcinoma of the head and neck, and intractable psoriasis. This product is an anti-tumor drug.
Specification：
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correctly to prevent any damage in transit.
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- FOB to a port in China
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