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Antihistaminic drugs Chlorpheniramine maleate /CAS:113-92-8 CAS NO.113-92-8
- FOB Price: USD: 104.00-117.00 /Kilogram Get Latest Price
- Min.Order: 1 Kilogram
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- Available Specifications:
98%(1-10)Kilogram98%(10-20)Kilogram
- Product Details
Keywords
- Chlorpheniramine maleate
- 2-Picoline-->Maleic acid-->Bromoacetaldehyde diethyl acetal-->2-(4-Chlorobenzyl)pyridine
- 113-92-8
Quick Details
- ProName: Antihistaminic drugs Chlorpheniramine ...
- CasNo: 113-92-8
- Molecular Formula: C20H23ClN2O4
- Appearance: White Solid
- Application: An antagonist of the histamine H1-rec...
- DeliveryTime: Shipped in 15 days after payment
- PackAge: according to customers' requirements
- Port: China main port
- ProductionCapacity: 10000 Metric Ton/Month
- Purity: 98% MIN
- Storage: -20°C Freezer
- Transportation: Air, sea, land transport
- LimitNum: 1 Kilogram
- Residue on Ignition: 0.10% max
- Heavy Metal: ≤0.002%
- Valid Period: 2 years
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Details
Introduction:
1.Name:Chlorphenamine Maleate
2.Cas No:113-92-8
3.MF:C16H19ClN2.C4H4O4
4.MW.:390.87
5.Appearance:white crystalline powder
6.Other Names: Chlorphenamine hydrogen maleate; 1-p-Chlorophenyl-1-(2-pyridyl)-3-dime
7.appearance:white powder
8.meilting point :131.5~135°C
9.Loss on drying: meet therequirment
10.residue on ignition: less than 0.1%
11.Assay: not less than 98.5%
12.usage: Anti-Ulcerative colitis
Chlorpheniramine Maleate is a small molecule H1-receptor antagonist. Increased ornithine decarboxylase activity induced in an is chemia-reperfusion state was attenuated by Chlorpheniramine Maleate, indicating that this increase is mediated through engagement of the H1-receptor by histamine. Histamine-mediated repair of intestinal mucosa following ischemia-reperfusion was also demonstrated to operate through the H1-receptor with Chlorpheniramine Maleate. Induction of ornithine decarboxylase was blocked by Chlorpheniramine Maleate in Ehrlich carcinoma and MCF-7 cells. The positive inotropic effect of H1-receptor stimulation by histamine on protein tyrosine phosphorylation in guinea pig left atrium was antagonized by Chlorpheniramine Maleate.
Function:
Chlorpheniramine Maleate is a small molecule H1-receptor antagonist. Increased ornithine decarboxylase activity induced in an is chemia-reperfusion state was attenuated by Chlorpheniramine Maleate, indicating that this increase is mediated through engagement of the H1-receptor by histamine. Histamine-mediated repair of intestinal mucosa following ischemia-reperfusion was also demonstrated to operate through the H1-receptor with Chlorpheniramine Maleate. Induction of ornithine decarboxylase was blocked by Chlorpheniramine Maleate in Ehrlich carcinoma and MCF-7 cells. The positive inotropic effect of H1-receptor stimulation by histamine on protein tyrosine phosphorylation in guinea pig left atrium was antagonized by Chlorpheniramine Maleate.
Application:
It is the strongest antihistamine
First, the sedative effect is weak and has certain anticholinergic effect. It is an antihistamine for hydrocarbon. It is characterized by strong anti-histamine, small dosage, less side effects and applicable to children. It is used in allergic diseases, insect bites and allergic reactions. The compatibility with antipyretic analgesics is used to cure colds.
Specification:
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Production Inspection Process:
Our Group service includes regular and thorough inspections throughout the manufacturing process, eliminating the need to employ additional quality control inspectors.
- Raw material before any production begins
- Pre-production samples to ensure specifications are being met
- In-process to confirm that standards are maintained
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correctly to prevent any damage in transit.
We can help operating split shipments, meeting the factory minimum quantity but ship them in 2 or 3 shipments with required gaps among. This allows you to move stock through your business without taking up space and capital.
We will arrange the subsequent shipments from our factory to your warehouse.
We can consolidate your small orders from multiple factories, delivering all at the same time to you or your customers,using the most cost-effective route available. At the time of order placement, we will offer details to you about the volume of each component part and what size container will be used.
We can offer the complete package from concept to delivery; arranging everything up until products arrive at your own door or distribution hub.
Delivery can be offered.
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- FOB to a port in China
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Whether you have your own freight-forwarder or you would like to organize shipment; whether you require delivery FOB in China or CIF to a port near you, we are glad to quote and supply whichever way you choose. Please feel free to discuss all options with us.
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