Name: Ceftiofur sodium
CAS No.: 104010-37-9
Specification: 99%
Documentation: DMF OPEN
Formula: C19H16N5NaO7S3
Molecular Weight: 545.55
Density: 1.81 g/cm3
Solubility: freely soluble In Water
Appearance: off-white or yellowish crystalline powder
Synonyms:Ceftiofur sodium salt;Sodium ceftiofur;(6R-(6alpha,7beta(Z))-7-(((2-Amino-4-thiazolyl)(methoxyimino)acetyl)amino)-3-(((2-furanylcarbonyl)thio)methyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid sodium salt;CCRIS 7601;Naxcel;Sodium (6R,7R)-7-(2-(2-amino-4-thiazolyl)glyoxylamido)-3-(mercaptomethyl)-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylate, 7(sup 2)-(Z)-(O-methyloxime), 2-furoate (ester);
Ceftiofur sodium is a veterinary clinical special antibiotic for cephalosporins and is a broad-spectrum antibacterial. It has strong antibacterial activity against Gram-positive bacteria and Gram-negative bacteria. Ceftiofur acts on the transcriptional peptidase to block the synthesis of the peptide, and the bacterial cell wall is deleted to achieve bactericidal action. Ceftiofur has a stable β-lactam ring and is not easily destroyed by drug-resistant bacteria. It can act on Gram-positive and Gram-negative bacteria producing β-lactamase.
Ceftiofur sodium is a compound preparation for bactericidal, anti-inflammatory, antipyretic and analgesic. Ceftiofur sodium is a third-generation cephalosporin antibiotic for veterinary clinics. It has a broad-spectrum and high-efficiency bactericidal effect. For G+ and G-bacteria, including β- The strains of lactamy mildew have a strong killing effect, and ceftiofur sodium absorbs rapidly after muscle and subcutaneous injection, reaching an effective peak concentration of 0.5-0.3 hours. It is widely distributed throughout the body and is the best new drug for clinical treatment of bacterial diseases.
Ceftiofur sodium is mainly used for serious infection of bacteria and Escherichia coli and Salmonella in poultry.
1. High temperature and high fever caused by systemic or local infection of viruses and bacteria, coughing, gasping, difficulty in breathing, redness and purpleness of the skin, purple hair in the ears, ulceration of the mouth and hoof, abortion of abortion, circling, hind limb paralysis, no food, no lying Start, constipation and diarrhea.
2, infectious pleurisy, actinomycetes, Pasteurella multocida, Streptococcus mutans, piglet yellow and white peony, Salmonella, Haemophilus parasuis, atrophic rhinitis, chlamydia and so on.
3, livestock prenatal and postpartum high fever, endometritis, mastitis, no milk and less milk syndrome, laminitis, rot rot, bovine bacillus, transport fever, pneumonia, nasal atrophy, etc.