Creatine CAS NO.57-00-1

English name: Creatine

Molecular formula: C4H9N3O2

Molecular weight: 131.13

Melting point ~295 °C (dec.)

Boiling point 242.43°C (rough estimate)

1. Increase the water content of muscle cells:

When creatine is first used, it is obvious that the muscles become bigger and stronger.This is because creatine causes the body's muscle cells to store more water;And when all the muscle cells absorb more water and increase the volume, the muscle will naturally become fuller and more visible.

2. Helps muscle cells store energy:

Human muscle fibers contain two different forms of creatine: unbonded creatine and phospho-containing creatine, which accounts for about two-thirds of total creatine.When muscles contract to produce movement, the body USES a compound called ATP as its energy source.Unfortunately, the muscle cells of the human body can only supply ATP energy for rapid contraction less than 10 seconds. More ATP is needed to produce sustained motion, and the phosphocreatine, which is present in the muscle, sacrifices its phosphate to allow ATP to be resynthesized.Therefore, if there is more creatine in the muscle, the muscle has more potential strength to exert.

In addition, the exhaustion of creatine supplementation can also help the muscle cell rejuvenation, the reason is that when the muscle of the ATP energy depletion, the body also yao せ contributed to my restore ð « ? after TP generation system (glycolysis) and produce Lactic acid (Lactic aciA large amount of lactic acid is produced when the body is exercising vigorously, which causes muscle soreness and fatigue.If more phosphocreatine can be stored in muscles to supply ATP, the body will reduce the production of lactic acid and reduce the fatigue of muscle cells, allowing us to exercise longer and more explosive force.

3. Increase protein biosynthesis:

Creatine intake allows the body to use more protein to build muscle.And two protein structures in muscles;Actin and myosin are the main components that cause muscle fibers to contract and move.Therefore, if enough creatine can be added, the body can reduce the energy consumption of protein and synthesize more actin and myosin cells, muscles will naturally become stronger and more powerful.

Application 1. Can be used to promote the skeletal muscle to adapt to strenuous exercise and to combat fatigue and excessive nutrition supplements in weak individuals.

2. Can be used to prepare drugs to treat heart disease and respiratory insufficiency.

3. Preparation of pharmaceutical preparations containing human growth hormone.

4. It can be used for compounding a new healthy food, which has the effect of anti-aging and restoring physical strength.

5. Biochemical reagents.

An overview of creatine, its physical and chemical properties, preparation methods, pharmacological effects, applications, and side effects are edited by ding hong of Chemicalbook.(2015-11-04)

Side effects 1. By-products

Low purity creatine is not only ineffective, but also harmful to human health. The harmful substance is mainly a derivative called dicyandiamide, which can increase the excretion burden of the kidney.The purity of 99.99% creatine contained less than 20PPM dicyandiamide.

2. Energy source

Muscles move by breaking down adenosine triphosphate (ATP) to provide energy.At high intensity, ATP breaks down in a matter of seconds, meaning it only provides energy for a few seconds.Aerobic exercise can be broken down by carbohydrates, fats and other aerobic synthesis.But in anaerobic exercise, creatine begins to interfere with energy metabolism when there is not enough oxygen.It combines with phosphoric acid to form phosphocreatine phosphate (CP), rapidly replenishing ATP.In theory, the more creatine is stored, the more CP is synthesized, the longer ATP can be supplied, and the longer muscles can sustain themselves during high-intensity exercise.In convalescence, creatine synthesis still depends on carbohydrate and other aerobic energy, so, carbohydrate intake not too little.Otherwise, creatine decomposition, not synthesis, the next training will not be able to supply energy.

Risk 3.

Because creatine can replenish energy quickly.Therefore, it is easy to overtrain in training.

Use biochemical research, health care products