An oral hypoglycemic agent 1,1-Dimethylbiguanide hydrochlorideCAS:1115-70-4 CAS NO.1115-70-4

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99%(1-10)Kilogram32/Kilogram1USD99%(10-20)Kilogram28/Kilogram10USD

Product Details

Keywords

1,1-Dimethylbiguanide hydrochloride
1115-70-4
Dimethylamine-->Dicyanodiamide

Quick Details

ProName: An oral hypoglycemic agent 1,1-Dimethy...
CasNo: 1115-70-4
Molecular Formula: C4H12ClN5
Appearance: White powder
Application: Anti-diabetic and anti-cancer activity...
DeliveryTime: Shipped in 15 days after payment
PackAge: according to customers' requirements
Port: China main port
ProductionCapacity: 10000 Metric Ton/Month
Purity: 99%
Storage: Store at RT.
Transportation: Air, sea, land transport
LimitNum: 1 Kilogram
Related Substances: 0
Residue on Ignition: 0.1% max
Heavy Metal: 10ppm max
Valid Period: 2 years

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Details

Introduction:

English name: Metformin HCL

Synonyms: Metformin Hydrochloride; 3- (diaminomethylidene) -1,1-dimethylguanidine hydrochloride (1: 1)

CAS-No.: 1115-70-4

Molecular Formula: C4H12ClN5

Molecular Weight: 165.62

EINECS: 214-230-6

Purity: 99%

Appearance: White crystalline or crystal powder

Applications: This product is lowering blood sugar medicine, Used for light diabetes.

Metformin hydrochloride is the first choice of first-line hypoglycemic agents, this class of drugs do not stimulate pancreatic β-cells, almost no effect on normal people, and type 2 diabetes significantly hypoglycemic effect. It does not affect insulin secretion, mainly through the promotion of peripheral tissue uptake of glucose, gluconeogenesis inhibition, reduce hepatic glycogen output, delayed glucose absorption in the intestine, thereby reducing the role of blood sugar.

Function:

1. Mainly for children, obese or overweight 2 type diabetes patients ,

2. Can also be used for type 1 diabetes, can reduce the amount of insulin,

3. Can also be used for the treatment of insulin resistance syndrome;

4. Because of its large response to the gastrointestinal tract, should be taken in the meal or after meals.

5. Renal impairment in patients disabled.

Main Application:

1.The product belongs to hypoglycemic agents. It can be used in patients with type Ⅱ diabetes to reduce fasting and postprandial hyperglycemia, HbAlc can be decreased by 1% to 2%, hypoglycemic mechanism of this product may be: I increase the sensitivity of peripheral tissues to insulin, increases insulin-mediated glucose utilization . II increase glucose utilization of non-insulin dependent tissues, such as brain, blood cells, kidney medulla, intestine, skin and the like. III inhibit hepatic gluconeogenesis effect, reduce hepatic glucose output. IV inhibit glucose uptake by intestinal cells.

2.Indications: For mild diabetes.

3.Metformin hydrochloride is an anti-diabetic agent, reducing blood glucose levels, and improving insulin sensitivity. Its metabolites (including the inhibition of hepatic gluconeogenesis) is activated through LKB1-AMPK (AMP-activated protein kinase) path.

4.Hypoglycemic agents, it is used for non-insulin-dependent diabetes. Rat oral LD50 of 1000 mg/kg.

Specification :

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Production Inspection Process:

Our Group service includes regular and thorough inspections throughout the manufacturing process, eliminating the need to employ additional quality control inspectors.

- Raw material before any production begins

- Pre-production samples to ensure specifications are being met

- In-process to confirm that standards are maintained

- Pre-shipping to ensure that the product arrives to the customer exactly as expected and is packaged

correctly to prevent any damage in transit.

We can help operating split shipments, meeting the factory minimum quantity but ship them in 2 or 3 shipments with required gaps among. This allows you to move stock through your business without taking up space and capital.

We will arrange the subsequent shipments from our factory to your warehouse.

We can consolidate your small orders from multiple factories, delivering all at the same time to you or your customers,using the most cost-effective route available. At the time of order placement, we will offer details to you about the volume of each component part and what size container will be used.

We can offer the complete package from concept to delivery; arranging everything up until products arrive at your own door or distribution hub.

Delivery can be offered.

- Utilizing your own freight-forwarder

- FOB to a port in China

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Whether you have your own freight-forwarder or you would like to organize shipment; whether you require delivery FOB in China or CIF to a port near you, we are glad to quote and supply whichever way you choose. Please feel free to discuss all options with us.