Anti-diabetic drug VogliboseCAS:83480-29-9 CAS NO.83480-29-9

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99%(1-4)Gram120/Gram1USD99%(5-10)Gram110/Gram5USD

Product Details

Keywords

Voglibose
83480-29-9
Anti-diabetic drug.

Quick Details

ProName: Anti-diabetic drug VogliboseCAS:83480-...
CasNo: 83480-29-9
Molecular Formula: C10H21NO7
Appearance: Colourless Crystalline Solid
Application: An alpha-Glucosidase inhibitor used as...
DeliveryTime: Shipped in 15 days after payment
PackAge: according to customers' requirements
Port: China main port
ProductionCapacity: 10000 Metric Ton/Month
Purity: 99%
Storage: Store at -20°C
Transportation: Air, sea, land transport
LimitNum: 1 Gram
Related Substances: <3.0%
Residue on Ignition: <1.0%
Heavy Metal: <0.002%
Valid Period: 2 years

Superiority

Voglibose is an oral hypoglycemic agents which can alleviate the postprandial hyperglycemia of diabetes patients. It is first successfully developed by the Takeda Company in Japan. It belongs to α-glucosidase inhibitor (a drug which can delay the intestinal absorption of carbohydrates to achieve hypoglycemic effect). Its mechanism of action is through inhibiting the activity of disaccharides hydrolase (α-glucosidase) which can hydrolyze disaccharide into monosaccharide inside the gut and thus delaying the digestion and absorption of sugar and further alleviating the postprandial hyperglycemia. In the assay of measuring the exhaled hydrogen of healthy adults given sucrose loading, the results have confirmed that this drug in its clinical dosage has an inhibitory effect on hyperglycemia.

Details

Introduction:

Voglibose is an oral hypoglycemic agents which can alleviate the postprandial hyperglycemia of diabetes patients. It belongs to α-glucosidase inhibitor (a drug which can delay the intestinal absorption of carbohydrates to achieve hypoglycemic effect). Its mechanism of action is through inhibiting the activity of disaccharides hydrolase (α-glucosidase) which can hydrolyze disaccharide into monosaccharide inside the gut and thus delaying the digestion and absorption of sugar and further alleviating the postprandial hyperglycemia. In the assay of measuring the exhaled hydrogen of healthy adults given sucrose loading, the results have confirmed that this drug in its clinical dosage has an inhibitory effect on hyperglycemia.

Application:

Voglibose can inhibit various Alpha glucose glycosides enzyme as maltose enzyme, and different maltose enzyme, and glucose starch starch enzyme and the sucrose enzyme of activity, delay sugar points of Digest and absorption, makes starch decomposition into oligonucleotide sugar as maltose (disaccharide), and malt three sugar and the paste fine (low poly sugar), sucrose decomposition into glucose and fructose of speed slows down, caused intestinal on glucose of absorption slow, to ease meal Hou high blood sugar.

Specification:

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