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an enzyme prosthetic group Pyridoxal 5'-phosphateCAS:41468-25-1 CAS NO.41468-25-1
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Keywords
- 41468-25-1
- Pyridoxal 5'-phosphate
- DL-Tryptophan
Quick Details
- ProName: an enzyme prosthetic group Pyridoxal 5...
- CasNo: 41468-25-1
- Molecular Formula: C8H12NO7P
- Appearance: Yellow Crystalline Powder
- Application: Pyridoxal 5-phosphate (PLP) (active f...
- DeliveryTime: within 3-5 working days upon the rece...
- PackAge: according to customers' requirements
- Port: china main port
- ProductionCapacity: 1000 Metric Ton/Month
- Purity: 99%
- Storage: 2-8°C
- Transportation: according to customers' requirements
- LimitNum: 1 Kilogram
- Residue on Ignition: 0.5%MAX
- Heavy Metal: 10ppm
- Voluntary Standards: GK
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Details
Introduction:
Product Name: Pyridoxal 5'-Phosphate
CAS No: 41468-25-1
EINECS No: 200-208-3
Molecular Formular: C8H12NO7P
Molecular Weight: 265.16
Appearance: Pale yellowish white crystalline powder
Pyridoxal-5’-phosphate monohydrate is a vitamin B6 metabolite that can modify lysyl and valyl residues in proteins. It has the ability to inhibit purinergic receptors and intracellular influx of Ca2+. Pyridoxal-5’-phosphate monohydrate can modify peptides and suppress their precursor ionization efficiency. Research shows that pyridoxal-5'-phosphate-dependent enzymes can be inhibited by cycloserine.
Function：
Pyridoxal 5'-Phosphate as a coenzyme in all transamination reactions, and in certain decarboxylation, deamination, and racemization reactions of amino acids.The aldehyde group of PLP forms a Schiff-base linkage (internal aldimine) with the ε-amino group of a specific lysine group of the aminotransferase enzyme. The α-amino group of the amino acid substrate displaces the ε-amino group of the active-site lysine residue in a process known as transaldimination. The resulting external aldimine can lose a proton, carbon dioxide, or an amino acid sidechain to become a quinoid intermediate, which in turn can act as a nucleophile in several reaction pathways.
Application：
1) Pyridoxal-5-Phosphate is used to treat Parkinson's disease
2) Promote the transaminase in transamination dopamine levels in the body
3) Used in the treatment of acute or chronic eczema dermatitis nettle examine pustular rash itching seborrheic eczema scaly rash drug eruption deficiency oral inflammation glossitis pregnancy reaction, asthma, etc
4) The main body of vitamin B6
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