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The best quality intermediates,Cinchonine,cas:118-10-5 CAS NO.118-10-5
- FOB Price: USD: 820.00-830.00 /Kilogram Get Latest Price
- Min.Order: 25 Kilogram
- Payment Terms: L/C,D/A,D/P,T/T,
- Available Specifications:
%(25-50)Kilogram%(100-200)Kilogram
- Product Details
Keywords
- 118-10-5
- Cinchonine
- D-CINCHONINE
Quick Details
- ProName: The best quality intermediates,Cinchon...
- CasNo: 118-10-5
- Molecular Formula: C19H22N2O
- Appearance: White crystal Powder
- Application: It is used as an antimalarial drug.
- DeliveryTime: Shipped in 15 days after payment
- PackAge: according to customers' requirements
- Port: China main port
- ProductionCapacity: 10000 Metric Ton/Month
- Purity: %
- Storage: Store below +30°C
- Transportation: Air, sea, land transport
- LimitNum: 25 Kilogram
Superiority
An alkaloid derived from the bark of the cinchona tree.
It is used as an antimalarial drug, and is the active ingredient in extracts of the cinchona that have been used for that purpose since before 1633.
Cinchonine is also a mild antipyretic and analgesic and has been used in common cold preparations for that purpose.
It was used commonly and as a bitter and flavoring agent, and is still useful for the treatment of babesiosis.
Cinchonine is also useful in some muscular disorders, especially nocturnal leg cramps and myotonia congenita, because of its direct effects on muscle membrane and sodium channels. The mechanisms of its antimalarial effects are not well understood.
Details
| Cinchonine Basic information | |
| Product Name: | Cinchonine |
| Synonyms: |
D-CINCHONINE;(+)-CINCHONINE;CINCHONINE;CINCHONAN-9-OL,(9S)-; (+)-cinconine;(8r,9s)-cinchonine;(9s)-cinchonan-9-o;(9S)-Cinchonan-9-ol |
| CAS: | 118-10-5 |
| MF: | C19H22N2O |
| MW: | 294.39 |
| EINECS: | 204-234-6 |
| Product Categories: |
Quinoline Alkaloids;Quinolinecarboxylic Acids, etc.;Quinolines;Synthetic Organic Chemistry; Asymmetric Synthesis;Chiral Resolution Reagents;Chiral Resolving ReagentsChiral Catalysts, Ligands, and Reagents;Cinchona Alkaloids;Privileged Ligands and Complexes;Aromatics; Chiral Reagents;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;Miscellaneous Natural Products;chiral;Alkaloids;Biochemistry;for Resolution of Acids;Optical Resolution;API; DOBUTREX |
| Mol File: | 118-10-5.mol |
| Cinchonine Chemical Properties | |
| Melting point | 260-263 °C |
| alpha | 224 º (c=0.5, alcohol) |
| Boiling point | 436.16°C (rough estimate) |
| density | 1.0863 (rough estimate) |
| refractive index | 223 ° (C=0.5, EtOH) |
| storage temp. | Store below +30°C. |
| solubility | 0.25g/l |
| form | Micro-Crystalline Powder |
| pka | 5.85, 9.92(at 25℃) |
| color | White to light beige |
| PH | 9.0 (0.25g/l, H2O, 20℃)(as aqueous solution) |
| optical activity | [α]23/D +228°, c = 0.5 in ethanol |
| Water Solubility | Insoluble |
| Sensitive | Light Sensitive |
| Merck | 142287 |
| BRN | 89689 |
| Stability: | Stable, but may be light sensitive. Incompatible with strong oxidizing agents. |
It is used as an antimalarial drug, and is the active ingredient in extracts of the cinchona that have been used for that purpose since before 1633.
Cinchonine is also a mild antipyretic and analgesic and has been used in common cold preparations for that purpose.
It was used commonly and as a bitter and flavoring agent, and is still useful for the treatment of babesiosis.
Cinchonine is also useful in some muscular disorders, especially nocturnal leg cramps and myotonia congenita, because of its direct effects on muscle membrane and sodium channels. The mechanisms of its antimalarial effects are not well understood.
