7-Hydroxyquinolinone 70500-72-0 CAS NO.70500-72-0

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7-Hydroxyquinolinone Basic information

Product Name:	7-Hydroxyquinolinone
Synonyms:	2,7-DIHYDROXYQUINOLINE;7-HYDROXYQUINOLINE-(1H)-2-ONE;3,4-Dihydro-7-hydroxyquinoline-2(1H)-one;7-Hydroxyquinolin-2(1H)-one;3,4-DIHYDRO-7-HYDROXY-2(1H)-QUINOLINE;7-Hydroxycarbostyril;7-HYDROXY-2-QUINOLINONE;7-HYDROXY-1H-QUINOLIN-2-ONE
CAS:	70500-72-0
MF:	C9H7NO2
MW:	161.16
EINECS:	812-453-9
Product Categories:	Aromatics Compounds;Quinoline;Aromatics;Intermediates & Fine Chemicals;Pharmaceuticals;Heterocycles
Mol File:	70500-72-0.mol

7-Hydroxyquinolinone Chemical Properties

Melting point	187-192°C
Boiling point	426.8±45.0 °C(Predicted)
density	1.337±0.06 g/cm3(Predicted)
storage temp.	Inert atmosphere,Room Temperature
solubility	DMSO (Slightly), Methanol (Slightly, Sonicated)
pka	9.32±0.20(Predicted)
form	Solid
color	Off-White to Pale Yellow
CAS DataBase Reference	70500-72-0(CAS DataBase Reference)

Safety Information

HS Code

29334900

MSDS Information

7-Hydroxyquinolinone Usage And Synthesis

Chemical Properties	Off-White Solid
Uses	7-Hydroxyquinolone is a substituted carbostyril derivative used as a pharmaceutical intermediate. It is an impurity of aripiprazole quinolinone.
Uses	A substituted carbostyril derivative as pharmaceutical intermediate. Aripiprazole Quinolinone Impurity

Function&Application

[Use 1] for the synthesis of prostaglandins, certain antibiotics, auxiliary drugs for the hypolipidemic drugs lovastatin and simvastatin

[Use 2] Used as a pharmaceutical intermediate and used in organic synthesis, as a hydroxyl protecting agent in organic synthesis

[Use 3] Silanization agent. As a hydroxy protecting agent in organic synthesis, derivatizing reagents are used for analysis and preparation. Protect tertiary alcohols. Reacts with an alcohol to form a silyl ether. The conformation of the cholesterol derivative was determined. Synthetic prostaglandins, auxiliary materials for certain antibiotics, the lipid-lowering drugs Lovastatin and Simvastatin.

 

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