2-Oxazolidone 497-25-6 CAS NO.497-25-6

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2-Oxazolidone Basic information

Product Name:	2-Oxazolidone
Synonyms:	2-Oxotetrahydro-1,3-oxazole;2-Oxazolinone;2-Oxazolidone,98%;2-Oxazolidone, 98% 100GR;2-Oxazolidone, 98% 25GR;2-Oxo-1,3-oxazolidine;NSC 35382;NSC 38240
CAS:	497-25-6
MF:	C3H5NO2
MW:	87.08
EINECS:	207-840-9
Product Categories:	Building Blocks;Heterocyclic Building Blocks;Oxazolines/Oxazolidines;Building Blocks;Chemical Synthesis;Heterocyclic Building Blocks;Heterocyclic Compounds;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals
Mol File:	497-25-6.mol

2-Oxazolidone Chemical Properties

Melting point	83-87 °C(lit.)
Boiling point	220 °C48 mm Hg(lit.)
density	1.2736 (rough estimate)
refractive index	1.4940 (estimate)
Fp	220°C/48mm
storage temp.	Sealed in dry,Room Temperature
solubility	Chloroform (Slightly, Heated), Methanol (Slightly)
pka	12.78±0.20(Predicted)
form	Crystals or Powder
color	Off-white to yellow-beige
Water Solubility	Soluble in water.
BRN	106251
CAS DataBase Reference	497-25-6(CAS DataBase Reference)
NIST Chemistry Reference	Oxazolidin-2-one(497-25-6)
EPA Substance Registry System	2-Oxazolidinone (497-25-6)

Safety Information

Hazard Codes	Xn,Xi
Risk Statements	22-36-43-40-36/37/38
Safety Statements	26-36/37-37-36
WGK Germany	3
RTECS	RQ2450000
TSCA	Yes
HS Code	29322980
Toxicity	TDLo orl-mus: 1000 mg/kg:ETA BCPCA62,168,59

MSDS Information

Provider	Language
Oxazolidin-2-one	English
SigmaAldrich	English
ACROS	English
ALFA	English

2-Oxazolidone Usage And Synthesis

Chemical Properties	off-white to yellow-beige crystals or powder
Uses	As an oxazole derivative used as an antibiotic,  2-Oxazolidone is also used in the preparation of compounds with antitumor activity and as a metabolite of Furazolidone (F864100).
Uses	An oxazole derivative used as an antibiotic. It is also used in the preparation of compounds with antitumor activity. A metabolite of Furazolidone (F864100).
Definition	ChEBI: An oxazolidinone that is 1,3-oxazolidine with an oxo substituent at position 2.
Safety Profile	Questionable carcinogen with experimental tumorigenic data. When heated to decomposition it emits toxic fumes of NOx.
Purification Methods	Crystallise it from *benzene, dichloroethane, CHCl3 or EtOH. It is a cyclic urethane, and as such it is not very stable. [Katritzky et al. J Chem Soc Perkin II 145 1990, Beilstein 27 H 135, 27 II 259, 27 III/IV 2516.]

2-Oxazolidone Preparation Products And Raw materials

Raw materials	Ethanolamine-->Ethenimine (9CI)-->N-Benzyloxybenzamide-->2-Oxazolidinone,3-benzoyl--->2-bromoethylamine-->O-Benzylhydroxylamine-->PROPARGYLAMINE-->Urethane-->3-TRIMETHYLSILYL-2-OXAZOLIDINONE-->1-(Trimethylsiloxy)cyclopentene
Preparation Products	Furazolidone-->Lomustine-->3-AMINO-2-OXAZOLIDINONE-->N,N'-bis-(2-Chloroethyl)urea-->2-Chloroethyl isocyanate-->3,4-METHYLENEDIOXYPHENETHYLAMINE HYDROCHLORIDE

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Production Inspection Process:

Our Group service includes regular and thorough inspections throughout the manufacturing process, eliminating the need to employ additional quality control inspectors.

- Raw material before any production begins

- Pre-production samples to ensure specifications are being met

- In-process to confirm that standards are maintained

- Pre-shipping to ensure that the product arrives to the customer exactly as expected and is packaged

correctly to prevent any damage in transit.

 

Warehousing：

    We can help operating split shipments, meeting the factory minimum quantity but ship them in 2 or 3 shipments with required gaps among. This allows you to move stock through your business without taking up space and capital.

We will arrange the subsequent shipments from our factory to your warehouse.

We can consolidate your small orders from multiple factories, delivering all at the same time to you or your customers,using the most cost-effective route available. At the time of order placement, we will offer details to you about the volume of each component part and what size container will be used.

 

Delivery：

   We can offer the complete package from concept to delivery; arranging everything up until products arrive at your own door or distribution hub.

   Delivery can be offered.

    - Utilizing your own freight-forwarder

    - FOB to a port in China

    - CIF to a port near you

   Whether you have your own freight-forwarder or you would like to organize shipment; whether you require delivery FOB in China or CIF to a port near you, we are glad to quote and supply whichever way you choose. Please feel free to discuss all options with us.

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